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. 2021 Oct 12;12:645500. doi: 10.3389/fmicb.2021.645500

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Copyright © 2021 Zhao, Zhou, Dong, Zhang, Xie, Tian and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lactobacillus reuteri is associated with RTX-induced intestinal mucositis. (A) LEfSe analysis of differentially abundant species in RTX-treated mice on day 0 (R1) and day 7 (R2). (B) LDA scores of differentially abundant species in the intestine before and after RTX treatment showing only the groups with an LDA threshold > 3.6. (C) The relative abundance of significantly different bacteria in control and RTX treatment groups. (D) qPCR results of different bacteria in feces samples. Data are shown as the mean ± SEM. *p < 0.05, **p < 0.01.