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. 2021 Oct 12;8:744032. doi: 10.3389/fvets.2021.744032

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Copyright © 2021 Mei, Xin, Liu, Lin, Xian, Zhang, Hu, Xia, Wang and Lyu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Morphology of CMT-1026 cells. (A) Purified CMT-1026 cells, detected with inverted microscopy (10×). (B) CMT-1026 pellet; Diff-Quik staining (40×). Malignant cancer cells with epithelial morphology, marked anisokaryosis, and multinucleated giant cells. (C) Ultrastructural experiments revealed that CMT-1026 contained multiple organelles, mitochondria, secretory vacuoles, and endoplasmic reticulum. (D) Degenerated CMT-1026 cells, showing shrunken nuclei, and abundant proteinaceous secretion.