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. 2021 Oct 12;11:604882. doi: 10.3389/fonc.2021.604882

Table 3.

Multivariable regression for OS.

β HR se(β) Z P
Age 0.014 1.010 0.001 15.150 <0.0001
Sex
 Female Ref
 Male 0.082 1.090 0.023 3.540 0.0004
Tumor site
 Colon, unknown Ref
 Left colon 31.34 5.05×105 1.79×102 0.073 0.9414
 Overlapping lesion 34.22 6.74×105 1.79×102 0.075 0.9401
 Right colon 33.83 6.48×105 1.79×102 0.075 0.9403
 Transverse colon 33.99 6.58×105 1.79×102 0.075 0.9402
Histological type
 Adenocarcinoma Ref
 Not adenocarcinoma 0.160 1.170 0.042 3.810 0.0001
Tumor differentiation grade
 II Ref
 IV 0.544 1.720 0.052 10.510 <0.0001
 I -0.408 0.665 0.056 -7.230 <0.0001
 III 0.385 1.470 0.027 14.080 <0.0001
T category
 T0 Ref
 T1 -0.399 0.671 1.000 -0.397 0.6916
 T2 -0.925 0.397 1.010 -0.917 0.3589
 T3 -0.556 0.573 1.010 -0.554 0.5800
 T4 -0.281 0.755 1.010 -0.280 0.7794
 TX -0.383 0.682 1.000 -0.382 0.7026
N category
 N0 Ref
 N1 0.151 1.160 0.033 4.618 <0.0001
 N2 0.455 1.580 0.037 12.460 <0.0001
 NX 0.166 1.180 0.051 3.281 0.0010
Bone metastasis
 No Ref
 Yes 0.362 1.440 0.056 6.426 <0.0001
Brain metastasis
 No Ref
 Yes 0.432 1.540 0.125 3.460 <0.0001
Lung metastasis
 No Ref
 Yes 0.278 1.320 0.030 9.285 <0.0001
Tumor deposit
 No Ref
 Unknown 0.197 1.220 0.032 6.250 <0.0001
 Yes 0.112 1.120 0.038 2.943 0.0032
Tumor size
 0-1cm Ref
 1-5cm 0.296 1.340 0.231 1.281 0.2003
 unknown -0.082 0.921 0.037 -2.255 0.0241
Surgery
 No Ref
 Yes -0.806 0.447 0.049 -16.462 <0.0001
Chemotherapy
 No Ref
 Yes -1.086 0.338 0.026 -42.532 <0.0001

OS, overall survival; HR, hazard ratio; CI, confidence interval.