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. 2021 Oct 12;9:721676. doi: 10.3389/fcell.2021.721676

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Copyright © 2021 Yang, Ma and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation between lncRNA expression and immune infiltration. (A) Correlation analysis of immune-related lncRNA expression and the infiltration of aDCs, B cells, CD8+ T cells, cytotoxic cells, DCs, eosinophils, iDCs, macrophages, mast cells, neutrophils, NK CD56bright cells, NK CD56dim cells, NK cells, pDCs, T cells, T helper cells, Tcm, Tem, Tfh, Tgd, Th1 cells, Th17 cells, Th2 cells, and Tregs. (B) Spearman correlation analysis of TMB/MSI and immune-related lncRNA expression. Horizontal axis represents gene expression distribution. Ordinate represents TMB/MSI score distribution. The density curve on the right represents the TMB/MSI score distribution trend. The upper density curve represents the gene expression distribution trend. The uppermost value represents the correlation p-value, correlation coefficient, and correlation calculation method. p-Values of <0.05 were considered significant. The correlation coefficient range was (–1, 1), with a negative number representing a negative correlation between the expression of two genes and a positive value representing a positive correlation. The closer to 1 or –1, the stronger the correlation. The closer to 0, the weaker the correlation.