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. 2021 Oct 12;9:721676. doi: 10.3389/fcell.2021.721676

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Copyright © 2021 Yang, Ma and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CDKN2B-AS1 knockdown inhibits malignant biological behavior in EC cells. (A) CDKN2B-AS1 expression in Ishikawa and HEC-1A cell lines measured using RT-qPCR. (B) Effect of CDKN2B-AS1 expression on proliferation determined using EdU assays in Ishikawa and HEC-1A cells. (C) Transwell assays to determine the number of invading cells. (D) Nude mice bearing tumors. A specimen from each respective group is shown (n = 2 per group), ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001 vs. the NC group.