Table 2.
Outcomes for delivery of the standard NDPP and NDPP-Flex (N = 340)
| Unadjusted | Covariate-adjusted | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Standard NDPP | NDPP-Flex | P value | Standard NDPP | NDPP-Flex | P value | |||||
| Mean ± SE | n | Mean ± SE | n | Mean ± SE | n | Mean ± SE | n | |||
| Main models | ||||||||||
| Duration (1–365 days) | 169.90 ± 8.59 | 245 | 170.19 ± 13.35 | 95 | 0.986 | 166.71 ± 9.38 | 206 | 158.90 ± 15.20 | 85 | 0.674 |
| Sessions attended (1–25) | 10.84 ± 0.48 | 245 | 10.67 ± 0.72 | 95 | 0.848 | 10.57 ± 0.52 | 206 | 10.27 ± 0.84 | 85 | 0.772 |
| Physical activity (weekly minutes) | 177.36 ± 7.38 | 197 | 159.90 ± 11.31 | 82 | 0.190 | 175.64 ± 7.54 | 164 | 157.97 ± 11.91 | 72 | 0.231 |
| Weight loss (%) | 1.68 ± 0.20 | 245 | 1.20 ± 0.32 | 95 | 0.214 | 1.90 ± 0.24 | 164 | 1.46 ± 0.38 | 72 | 0.353 |
| HbA1c improvement (%) | 0.06 ± 0.03 | 127 | 0.21 ± 0.05 | 46 | 0.012 | 0.06 ± 0.03 | 98 | 0.22 ± 0.05 | 40 | 0.018 |
| Normoglycemia at follow-up (%) | 24.2% | 165 | 31.7% | 60 | 0.186 | 24.2% | 99 | 35.0% | 40 | 0.013 |
| Sensitivity analyses | ||||||||||
| For those with prepost HbA1c | ||||||||||
| Duration (1–365 days) | 175.27 ± 11.99 | 127 | 171.83 ± 18.04 | 46 | 0.880 | 175.24 ± 12.44 | 122 | 195.59 ± 21.70 | 45 | 0.551 |
| Sessions attended (1–25) | 11.12 ± 0.69 | 127 | 10.98 ± 1.01 | 46 | 0.921 | 11.00 ± 0.69 | 122 | 10.64 ± 1.21 | 45 | 0.807 |
| Physical activity (weekly minutes) | 165.89 ± 8.88 | 103 | 167.09 ± 16.56 | 41 | 0.946 | 171.07 ± 8.91 | 98 | 152.73 ± 14.73 | 40 | 0.313 |
| Weight loss (%) | 1.71 ± 0.26 | 127 | 1.17 ± 0.47 | 46 | 0.303 | 2.01 ± 0.30 | 98 | 1.33 ± 0.50 | 40 | 0.267 |
| HbA1c improvement (%) | 0.06 ± 0.03 | 127 | 0.21 ± 0.05 | 46 | 0.012 | 0.06 ± 0.03 | 98 | 0.22 ± 0.05 | 40 | 0.018 |
| Normoglycemia at follow-up (%) | 25.2% | 127 | 32.6% | 46 | 0.218 | 24.5% | 98 | 35.0% | 40 | 0.013 |
Data presented as unadjusted and adjusted mean ± SE and corresponding sample size, with boldface indicating significance at P < 0.05. Weight loss and HbA1c improvement were winsorized at the 5th and 95th percentiles. Adjusted models controlled for age, sex, race/ethnicity, baseline BMI, baseline HbA1c, pre-session attendance, class language, and coach, as well as retention, physical activity, and weight loss as applicable. Physical activity was collected starting at the 4th session (when introduced in the curriculum, per delivery guidelines [20]), limiting available data. HbA1c within ±12 months of participation was assessed as available in medical records for approximately half of participants.