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Incidence rates of HHF by risk category in the derivation and validation cohorts. Risk was categorized as low risk (0–3 points), intermediate risk (4–6 points), high risk (7–8 points), and very high risk (9–11 points). Incidence rates of HHF are shown for each risk category. The biomarker-based risk score identified a gradient of HHF risk with comparable incidence rates in each cohort.
