Table 1.
Baseline characteristics of postmenopausal women by T2DM from three cohorts
| All (n = 9,374) | T2DM (n = 1,237) | Non-T2DM (n = 8,137) | P | |
|---|---|---|---|---|
| Age (years) | 57.7 ± 8.6 | 58.9 ± 8.4 | 57.6 ± 8.6 | <0.0001 |
| Race/ethnicity | <0.0001 | |||
| Non-Hispanic White | 5,391 (57.5) | 436 (35.2) | 4,955 (60.9) | |
| Non-Hispanic Black | 3,016 (32.2) | 641 (51.8) | 2,375 (29.2) | |
| Other | 967 (10.3) | 160 (13.0) | 807 (9.9) | |
| Education | <0.0001 | |||
| High school or less | 5,027 (53.7) | 804 (65.1) | 4,223 (52.0) | |
| More than high school | 4,332 (46.3) | 432 (35.0) | 3,900 (48.0) | |
| Current smoking | 1,709 (18.2) | 176 (14.2) | 1,533 (18.9) | <0.0001 |
| Current alcohol drinking | 5,064 (54.0) | 407 (32.9) | 4,657 (57.2) | <0.0001 |
| BMI | ||||
| BMI (kg/m2) | 28.5 ± 6.3 | 32.4 ± 6.7 | 27.9 ± 6.0 | <0.0001 |
| BMI ≥30 kg/m2 | 3,263 (34.8) | 747 (60.5) | 2,516 (30.9) | <0.0001 |
| Blood pressure | ||||
| SBP (mmHg) | 125.1 ± 21.2 | 133.3 ± 22.5 | 123.9 ± 20.7 | <0.0001 |
| DBP (mmHg) | 71.1 ± 10.6 | 71.6 ± 10.9 | 71.0 ± 10.5 | 0.05 |
| SBP ≥140 mmHg or DBP ≥90 mmHg | 3,535 (37.8) | 680 (55.1) | 2,855 (35.1) | <0.0001 |
| Cholesterol | ||||
| Total (mg/dL) | 212.2 ± 40.9 | 212.3 ± 47.0 | 212.2 ± 39.9 | 0.96 |
| Total cholesterol ≥200 mg/dL | 5,542 (59.6) | 689 (57.5) | 4,853 (59.9) | 0.11 |
| Antihypertensive medication | 3,167 (33.8) | 743 (60.2) | 2,424 (29.8) | <0.0001 |
| Lipid-lowering medication | 2,294 (24.6) | 494 (40.2) | 1,800 (22.2) | <0.0001 |
| Menopausal age (years) | 45.4 ± 7.0 | 44.7 ± 7.6 | 45.6 ± 6.9 | <0.0001 |
| Early menopause (<45 years) | 3,447 (36.8) | 511 (41.4) | 2,936 (36.1) | 0.0004 |
| Menopausal type | ||||
| Natural | 5,757 (61.4) | 703 (56.8) | 5,054 (62.1) | 0.001 |
| Surgical | 3,519 (37.5) | 516 (41.7) | 3,003 (36.9) | |
| Not specified | 98 (1.1) | 18 (1.5) | 80 (1.0) | |
| Ever used hormone therapy | 5,051 (54.1) | 591 (48.1) | 4,460 (55.1) | <0.0001 |
| Ever pregnant | 8,609 (91.9) | 1,158 (93.7) | 7,451 (91.6) | 0.01 |
Data are mean ± SD or n (%). Missing n for covariates: education, 15; smoking, 4; BMI, 5; blood pressure, 10; cholesterol, 69; antihypertensive medication, 11; lipid-lowering medication, 40; and ever pregnant, 5. DBP, diastolic blood pressure; SBP, systolic blood pressure.