Table 3.
Summary of immune effector cell toxicities.
Number of subjects (%) | |
---|---|
Cytokine release syndrome | |
Grade 1 | 7 (35%) |
Grade 2 | 3 (15%) |
Time from infusion to CRS onset, days, median (range) | 4 (3-7) |
Neurotoxicity | |
Grade 1 – 2 | 4 (20%) |
Grade 3 – 4 | 1 (5%) |
Time to neurotoxicity onset, days, median (range) | 7 (5-9) |
Intensive Care Unit transfer | 1 (5%) |
Mechanical ventilation | 0 |
Post infusion tocilizumab, n (%) | 5 (25%) |
Post infusion corticosteroid, n (%) | 4 (20%) |
Post infusion anakinra, n (%) | 2 (10%) |
CRS: cytokine release syndrome |