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. 2021 Oct 12;12:745320. doi: 10.3389/fimmu.2021.745320

Table 3.

Summary of immune effector cell toxicities.

Number of subjects (%)
Cytokine release syndrome
 Grade 1 7 (35%)
 Grade 2 3 (15%)
Time from infusion to CRS onset, days, median (range) 4 (3-7)
Neurotoxicity
 Grade 1 – 2 4 (20%)
 Grade 3 – 4 1 (5%)
Time to neurotoxicity onset, days, median (range) 7 (5-9)
Intensive Care Unit transfer 1 (5%)
Mechanical ventilation 0
Post infusion tocilizumab, n (%) 5 (25%)
Post infusion corticosteroid, n (%) 4 (20%)
Post infusion anakinra, n (%) 2 (10%)
CRS: cytokine release syndrome