Table 3.
Anxiolytic activity of Me-RCR on elevated plus maze test in mice.
Group | Dose (mg/kg) | % of entry into open arm | % of time spent in open arm |
---|---|---|---|
Control | 10 mL/kg | 42.86 ± 2.23 | 38.46 ± 1.30 |
Diazepam | 1 | 79.50 ± 2.57∗∗ | 75.47 ± 2.44∗∗ |
Me-RCR 200 | 200 | 53.12 ± 3.14 | 50.63 ± 3.98 |
Me-RCR 400 | 400 | 54.17 ± 3.55∗ | 57.69 ± 3.17∗ |
Values are mean ± S.E.M. ∗p < 0.05 and ∗∗p < 0.01, significantly different from control; ANOVA followed Dunnett's test (n = 10, each group). Me-RCR, methanol extract of rhizome of C. recurvata.