Table 1.
Case | Age | Sex | Breed | Clinical features | Gross lesions |
---|---|---|---|---|---|
1 | 5 y | SF | American Shorthair | Recurrent ear infection, progressive neurologic signs (3-d course; lateral recumbency, stiff limbs, vocalization, anisocoria, nystagmus). Treated with clindamycin (10 mg/kg IV) and mannitol (0.5 g/kg IV). The cat had cardiorespiratory arrest. | CNS: opaque, white-to-green–tinged purulent exudate coating the meningeal surface of the caudodorsal aspect of the left cerebral hemisphere. |
Kidneys: unilateral focal chronic infarct. | |||||
2 | 2–3 mo | SF | Mixed breed | Upper respiratory signs, ocular discharge, neurologic signs (nystagmus, paraparesis, head tilt that progressed to lateral recumbency [unknown duration]). Treated with broad-spectrum antibiotics for the respiratory signs. The cat was found dead by the owner ~1 wk after having been introduced to its new home. | Skin: periocular yellow-to-brown crusts. |
Liver: white pinpoint foci. | |||||
3 | 2 mo | M | Mixed breed | Upper respiratory signs, sneezing, ocular and nasal discharge, and lethargy (unknown duration). No specific neurologic signs observed by the owner. Treated with broad-spectrum antibiotics for the respiratory signs. The cat was found dead by the owner a day after it had still been seen playing with the other kittens. | CNS: purulent exudate expanding the subdural space on the dorsal and ventrolateral aspect of the right cerebral hemisphere and interhemispheric fissure, and circumferentially around spinal cord segment C1. |
Nasal cavity and frontal sinuses were filled with mucopurulent exudate. | |||||
Skin: periocular and nasal dark brown crusts. | |||||
Thymus: inconspicuous. | |||||
Intestines: mild nematodiasis (Toxocara cati). |
CNS = central nervous system; IV = intravenous; M = intact male; SF = spayed female.