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. 2021 Oct 12;27:1609811. doi: 10.3389/pore.2021.1609811

TABLE 3.

Correlation between SIRI and chemotherapy.

Parameters Low SIRI <1.21 High SIRI ≥1.21 χ2 P Value
Cases (n) Number (%) 62 45
NACT regimens
 SOX 35 (32.7%) 17 (27.4%) 18 (40.0%) 7.151 0.028
 XELOX 56 (52.3%) 39 (62.9%) 17 (37.8%)
 Others a 16 (15.0%) 6 (9.7%) 10 (22.2%)
Preoperative chemotherapy times
 <3 57 (53.3%) 38 (61.3%) 19 (42.2%) 3.809 0.051
 ≥3 50 (46.7%) 24 (38.7%) 26 (57.8%)
Postoperative chemotherapy regimens
 SOX 32 (29.9%) 16 (25.8%) 16 (35.5%) 2.103 0.717
 XELOX 41 (38.3%) 26 (41.9%) 15 (33.3%)
 Others a 20 (18.7%) 13 (21.0%) 7 (15.6%)
 No 14 (13.1%) 7 (11.3%) 7 (15.6%)
Postoperative chemotherapy times
 0 14 (13.1%) 7 (11.3%) 7 (15.6%) 2.198 0.333
 <4 51 (47.7%) 27 (43.5%) 24 (53.3%)
 ≥4 42 (39.2%) 28 (45.2%) 14 (31.1%)
Response
 CR 9 (8.4%) 7 (11.3%) 2 (4.4%) 7.488 0.112 b
 PR 72 (67.3%) 45 (72.6%) 27 (60.0%)
 SD 7 (6.5%) 4 (6.4%) 3 (6.7%)
 PD 19 (17.8%) 6 (9.7%) 13 (28.9%)
a

DCF, docetaxel, cisplatin, and fluorouracil and other fluoropyrimidine-based adjuvant chemotherapy; ECF, epirubicin, cisplatin, and fluorouracil; FOLFOX, folinic acid, oxaliplatin, and fluorouracil; TCF, paclitaxel, cisplatin, and fluorouracil; TF, docetaxel and fluorouracil; TS, paclitaxel and S-1.

b

Performed using the Fisher’s exact test.