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(A) Endosomal escape behavior of aX-Td@bsiRNA incubated for 10 h analysed by confocal laser scanning microscopy. Scale bar = 10 μm. All data are expressed as the mean ± SD, n = 3. (B) The Pearson correlation coefficients between Cy five and endosomes were calculated by Image J software. The significance of the differences (∗P < 0.05 versus lipo3000@siRNA group, ∗∗P < 0.01 versus lipo3000@siRNA group, #P < 0.05 versus 2X-Td@2siRNA group) was evaluated by two-tailed Student’ s t-test.
