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. 2021 Mar 24;6(2):e00045-21. doi: 10.1128/mSphere.00045-21

FIG 1.

FIG 1

Survival of outbred CD1 mice after subcutaneous (SQ) challenge with hvKp2, hvKp94, and cKp1. (A) The mice were challenged with 2.6 × 102 CFU of hvKp2 and 2.75 × 102 CFU of hvKp94. (B) The mice were challenged with 2.8 × 103 CFU of hvKp2, 3.15 × 103 CFU of hvKp94, and 2.58 × 103 CFU of cKp1. (C) The mice were challenged with 2.85 × 104 CFU of hvKp94, 3.15 × 105 CFU of hvKp94, and 2.85 × 106 CFU of hvKp94. (D) The mice were challenged with 2.48 × 107 CFU of hvKp94, 2.5 × 107 CFU of cKp1, and 3.2 × 108 CFU of cKp1. Strains were grown overnight in LB medium. An in extremis state or death was scored as nonsurvival. Total n = 10 (n = 5 in each of two independent experiments) for each titer for each strain. Values that are significantly different by the log rank (Mantel-Cox) test are indicated as follows: for panel A, ***, P = 0.0003; for panel B, ****, P < 0.0001; and for panel D, ***, P = 0.0003. ns, not significantly different.