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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Cytokine. 2021 Sep 27;148:155711. doi: 10.1016/j.cyto.2021.155711

Fig. 4. Network and pathway interactions in Chagas and rheumatic herat diseases.

Fig. 4.

Protein-protein network interactions were performed considering the molecules altered in CCC and RHD as compared to CONTROL group. Top panels of (A) and (B) show the networks resulting of the analysis for CCC and RHD, respectively. Dark and light green represent rub nodes. Different colors distinguish nodes with different numbers of interactions. Bottom tables show the pathways found using the generated by the Kyoto Encyclopedia of Genes and Genomes (KEGG) algorithm, showing general common pathways between CCC and RHD (grey rows), the correspondence between the top ten hits for CCC in the top 20 for RHD (yellow rows) and the pathways exclusive for CCC (red rows).