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. 2021 Sep 22;6(10):3496–3508. doi: 10.1021/acssensors.1c01403

Figure 5.

Figure 5

(a) A wearable sweat-sensing patch composed of four layers: a spiral-patterned microfluidic channel, a pair of parallel Au electrodes for sweat rate sensing, a parylene-C insulation layer, and ion-selective electrodes (i). A complete view of the device (ii). Real picture of the device worn on the user’s wrist (iii). Reproduced from ref (60). Copyright 2018 American Chemical Society. (b) Assembly of the parts of a wearable device on top of the skin, in this order: skin adhesive tape, microfluidics (in PDMS), and sensors (patterned also on the PDMS substrate) (i). Real image of the wearable device including electronics (ii). Schematics of the fluidics operation (iii). Adapted from ref (81). Copyright 2018 John Wiley and Sons. (c) Wearable devices with the sensors embedded in the microfluidic channel. First design proposed for detection of ions (i). Reproduced from ref (45) (https://pubs.acs.org/doi/abs/10.1021/acs.analchem.9b02126). Copyright 2019 American Chemical Society. Second design developed for glucose analysis (ii). Reproduced from ref (46) (https://pubs.acs.org/doi/10.1021/acs.analchem.0c02211). Copyright 2020 American Chemical Society. Third (and more advanced) prototype for lactate sensing (iii). Reproduced from ref (78) (https://pubs.acs.org/doi/abs/10.1021/acssensors.1c01009). Copyright 2021 American Chemical Society.