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. Author manuscript; available in PMC: 2021 Oct 26.
Published in final edited form as: Free Radic Biol Med. 2020 Jan 21;152:689–696. doi: 10.1016/j.freeradbiomed.2020.01.012

Table 1.

Aerobic exercise training outcomes in rats receiving dexamethasone

Experimental group Bodyweight (g) Body weight changec Adrenal gland weightd (g) Arterial pressuree (mmHg) Heart rate (bpm) Morphometric analysesf
Wistar Rats Week-0 a Week-8 b (g) SP DP MP CD number/mm 2 C:F ratio
Sedentary-Control 203.6±9.7 438.0±14.1 −2.3±2.5 10.9±0.7 106±6 91±3 96±6 426±12 192.6±16.3 0.90±0.02
Sedentary-Dex 203.2±6.4 204.2±6.4 −52.2±3.4* 6.2±0.2* 129±4* 119±3* 122±4* 429±26 152.7±8.8* 0.70±0.02*
Trained-Control 206.8±7.4 401±17.7 +0.2±4.5 9.9±0.5 110±3 101±5 104±4 398±12 238.8±13.3 1.00±0.04
Trained-Dex 205.8±5.2 434.8±8.5 −56.3±4.0* 6.2±0.5* 121±4 106±5 110±4 371±8 222.0±10.3 1.00±0.02

Wistar rats were trained as described in Materials and Methods.

a

Body weight was measured immediately after first Tmax and

b

after 8 weeks of training.

c

Difference in body weight at the end of 14 days of dexamethasone treatment.

d

Adrenal gland weight was measured at the end of the experiment.

e

Systolic (SP), diastolic (DP), and mean (MP) blood pressure.

f

Histological analysis of capillary density (CD) and capillary to fiber ratio (C:F ratio) in tibialis anterior muscle. The number of animals per group n=5–10. Values are mean±SEM,

*

p<0.05 for dexamethasone effects;

p<0.05 for training outcomes; statistical analysis was performed as described in methods.