Table 1.
Experimental group | Bodyweight (g) | Body weight changec | Adrenal gland weightd (g) | Arterial pressuree (mmHg) | Heart rate (bpm) | Morphometric analysesf | ||||
---|---|---|---|---|---|---|---|---|---|---|
Wistar Rats | Week-0 a | Week-8 b | (g) | SP | DP | MP | CD number/mm 2 | C:F ratio | ||
Sedentary-Control | 203.6±9.7 | 438.0±14.1 | −2.3±2.5 | 10.9±0.7 | 106±6 | 91±3 | 96±6 | 426±12 | 192.6±16.3 | 0.90±0.02 |
Sedentary-Dex | 203.2±6.4 | 204.2±6.4 | −52.2±3.4* | 6.2±0.2* | 129±4* | 119±3* | 122±4* | 429±26 | 152.7±8.8* | 0.70±0.02* |
Trained-Control | 206.8±7.4 | 401±17.7 | +0.2±4.5 | 9.9±0.5 | 110±3 | 101±5 | 104±4 | 398±12 | 238.8±13.3┼ | 1.00±0.04┼ |
Trained-Dex | 205.8±5.2 | 434.8±8.5 | −56.3±4.0* | 6.2±0.5* | 121±4 | 106±5┼ | 110±4┼ | 371±8┼ | 222.0±10.3┼ | 1.00±0.02┼ |
Wistar rats were trained as described in Materials and Methods.
Body weight was measured immediately after first Tmax and
after 8 weeks of training.
Difference in body weight at the end of 14 days of dexamethasone treatment.
Adrenal gland weight was measured at the end of the experiment.
Systolic (SP), diastolic (DP), and mean (MP) blood pressure.
Histological analysis of capillary density (CD) and capillary to fiber ratio (C:F ratio) in tibialis anterior muscle. The number of animals per group n=5–10. Values are mean±SEM,
p<0.05 for dexamethasone effects;
p<0.05 for training outcomes; statistical analysis was performed as described in methods.