Table 2.
Cox regression model for all patients and hepatitis C virus patients for prediction of mortality
|
All patients (n = 1193)
|
Propensity score matched (n = 98)
|
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|
Univariate
|
Multivariate
|
Univariate
|
Multivariate
|
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|
|
Exp (B)
|
Sig.
|
Exp (B)
|
Sig.
|
Exp (B)
|
Sig.
|
Exp (B)
|
Sig.
|
| Age (yr) | 1.028 | < 0.001 | 1.029 | < 0.001 | 1.022 | 0.183 | - | - |
| Gender (female) | 0.675 | < 0.001 | 0.865 | 0.42 | 0.488 | 0.05 | 0.714 | 0.110 |
| Body mass index (kg/m2) | 0.991 | 0.184 | - | - | 1.014 | 0.514 | - | - |
| Hypertension | 1.611 | < 0.001 | 0.843 | 0.386 | 2.87 | 0.004 | 2 | 0.051 |
| Diabetes mellitus | 1.394 | 0.001 | 1.208 | 0.277 | 1.06 | 0.864 | - | - |
| Human immune-deficiency virus | 1.797 | < 0.001 | 1.251 | 0.492 | 1.92 | 0.064 | - | - |
| Asthma | 0.864 | 0.341 | - | - | 1.39 | 0.357 | - | - |
| Chronic obstructive pulmonary disease | 1.435 | 0.013 | 1.043 | 0.879 | 1.222 | 0.591 | - | - |
| Hepatitis B infection | 1.984 | 0.237 | - | - | 1.04 | 0.962 | - | - |
| HCV | 2.224 | < 0.001 | 2.435 | 0.041 | 3.88 | 0.001 | 3.46 | 0.004 |
| Congestive heart failure | 1.4 | 0.02 | 1.249 | 0.356 | 1.253 | 0.545 | - | - |
| Coronary artery disease | 1.387 | 0.023 | 1.092 | 0.734 | 1.05 | 0.923 | - | - |
| End stage renal disease | 1.208 | 0.305 | - | - | 1.013 | 0.983 | - | - |
| Chronic kidney disease | 1.437 | 0.016 | 1.188 | 0.535 | 1.024 | 0.957 | - | - |
| Hemoglobin | 0.966 | 0.123 | - | - | 0.925 | 0.337 | - | - |
| Total white count | 1.006 | 0.376 | - | - | 1.004 | 0.736 | - | - |
| Platelets | 0.998 | < 0.001 | 0.999 | 0.438 | 0.999 | 0.525 | - | - |
| Neutrophilic count | 1.023 | 0.028 | 0.991 | 0.658 | 1.072 | 0.145 | - | - |
| Lymphocyte count | 0.993 | 0.641 | 1 | 0.163 | 1.000 | 0.976 | - | - |
| D-dimer | 1 | < 0.001 | 1.001 | < 0.001 | 1.000 | 0.09 | - | - |
| Lactate dehydrogenase | 1.001 | < 0.001 | 1.001 | 0.374 | 1.000 | 0.714 | - | - |
| High sensitivity C-reactive protein | 1.002 | < 0.001 | 1 | 0.553 | 0.999 | 0.788 | - | - |
| Ferritin | 1 | 0.002 | 1.053 | 0.028 | 1.000 | 0.902 | - | - |
| Prothrombin time (s) | 1.001 | 0.89 | - | - | 1.1 | 0.281 | - | - |
| Activated partial thromboplastin time (s) | 0.998 | 0.804 | - | - | 0.966 | 0.281 | - | - |
| Creatinine | 1.072 | < 0.001 | - | - | 1.08 | 0.91 | - | - |
| Alanine transaminase | 0.999 | 0.325 | - | - | 0.998 | 0.371 | - | - |
| Aspartate transaminase | 1 | 0.391 | - | - | 0.999 | 0.402 | - | - |
| Alkalaine phosphatase | 0.999 | 0.222 | - | - | 0.275 | 0.995 | - | - |
| Total bilirubin | 1.131 | 0.002 | 1.026 | 0.925 | 1.16 | 0.475 | - | - |
| Combined bilirubin | 1.327 | < 0.001 | 1.091 | 0.733 | 1.17 | 0.510 | - | - |
| Total protein | 0.932 | 0.235 | - | - | 0.892 | 0.560 | - | - |
| Albumin | 0.681 | < 0.001 | 0.933 | 0.678 | 0.613 | 0.114 | - | - |
| Procalcitonin | 1.014 | < 0.001 | 1.001 | 0.793 | 1.008 | 0.544 | - | - |
HCV: Hepatitis C virus.