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Pulmonary GH pharmacokinetic profile. Leukopenic mice were treated intratracheally with a single dose of 500 μg of Sph3h, PelAh, Ega3h-Pp, or Ega3h-HEK and then sacrificed at the indicated time points. Lung homogenates were assessed by Western blotting. Dots represent the means ± standard errors from band intensities normalized to total band intensity at 0 h from at least 1 independent experiment with ≥5 mice per time point.
