FIG 3.

Pangenome of Providencia rettgeri human and insect isolates. The seven inner layers correspond to the seven genomes, including the sequenced Nasonia isolates in maroon, previously published Drosophila isolate in purple, and human-associated genomes in blue. The bars in the inner circles show the presence of gene clusters (GCs) in a given genome with the outer green circle depicting known COGs (green) versus unknown (white) assignments. The outermost layer of color-coded lines and text highlights groups of GCs that correspond to the genome core or to group-specific GCs. Genomes are ordered based on their gene-cluster distribution across genomes, which is shown at the top right corner (tree). Central dendrograms depict protein cluster hierarchy when displayed as protein cluster frequency. The top horizontal layer underneath the tree represents host source (Nasonia, maroon; Drosophila, purple; human, blue).