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. 2021 Oct 26;21:563. doi: 10.1186/s12935-021-02229-8

Fig. 1.

Fig. 1

The overall structure of DNA-PKcs (PDB id: 6ZFP). The structural domains are colored according to the schematic shown below the structures. The N terminus is shown in purple, the circular cradle in orange, the FAT domain in teal, and the kinase domain in yellow. (Reference: Chaplin AK, Hardwick SW, Liang S et al. Dimers of DNA-PK create a stage for DNA double-strand break repair. Nature Structural & Molecular Biology 2021, 28(1):13–19.)