Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Oct 12;9:675356. doi: 10.3389/fcell.2021.675356

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Xu, Xiao, Fan, Ruan, Cheng, Tian, Chen, Chen and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Overexpression of BIRC5 alleviates the inhibitory effects of RFWD3 knockdown on colorectal cancer cells. (A–C) RKO cell models were subjected to the detection of cell proliferation (A), cell apoptosis (B) and colony formation (C). The alterations of cell migration were tested via transwell assay (D) and wound-healing assay (E). NC (OE + KD) as negative control; BIRC5 + NC-shRFWD3 as overexpressed BIRC5; shRFWD3 + NC-BIRC5 as RFWD3 downregulation; BIRC5 + shRFWD3 as simultaneously downregulated RFWD3 and overexpressed BIRC5. The data are expressed as mean ± SD. * P < 0.05, ** P < 0.01, *** P < 0.001.