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. Author manuscript; available in PMC: 2022 Jun 3.
Published in final edited form as: IEEE Open J Ultrason Ferroelectr Freq Control. 2021 Jun 3;1:1–10. doi: 10.1109/ojuffc.2021.3085539

Fig. 1.

Fig. 1.

Experimental setup and ultrasound pulse sequence. (a) The experimental setup comprises a 4-annular array FUS transducer coaligned with an imaging probe (P12–5) both driven by a Verasonics Vantage system. A water cone was used to acoustically couple the transducers with the phantom. A thermocouple was used to measure the temperature at the FUS focus. The picture shows an example of a displacement image generated by the acoustic radiation force. All analyses were performed within the ROI defined based on the FWHM hydrophone measurements in water. (b) Interleaved ultrasound pulse sequence observed in hydrophone acquisitions. The example shows four 25-Hz AM cycles generated by the FUS transducer and a magnification within the first AM cycle on the top right (A and B indicate the start and end times of the first AM cycle). Plane wave imaging sequences were acquired with sampling frequency of 14 kHz before the FUS pulses (FR1), then at 1 kHz interleaved with the FUS pulses (FR2), and finally at 100 Hz after the FUS pulses (FR3). Please note that the image in Fig. 1(a) is not to scale and is exaggerated in size to provide the information needed.