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. 2021 Oct 12;9:746932. doi: 10.3389/fcell.2021.746932

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Copyright © 2021 Shen, Liu, Lv and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Mutation genes with significant difference between high- and low-expression CLEC5A groups. (B) Analysis of co-mutation and exclusive mutations in the CLEC5A overexpression group. (C) The difference of tumor mutational burden (TMB) levels in high- and low-expression CLEC5A groups. (D) Genes with significantly increased copy number variation in CLEC5A overexpression group. (E) Functional analysis of genes with decreased copy number variation in CLEC5A overexpression group. **p < 0.01; *p < 0.05.