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. 2021 Oct 26;16(10):e0258983. doi: 10.1371/journal.pone.0258983

Table 4. Multivariable analysis for all-cause mortality, composite of mortality and cardiovascular (CV)-related re-admission, CV-related re-admission and heart failure (HF) admission with SSS.

Overall Mortality Composite of Mortality & CV Re-admission CV Re-admission HF Admission
HR P value HR P value HR P value HR P value
Clinical data + Attenuation correction
Gender 0.55 0.17 0.80 0.45 0.76 0.44 0.29 0.22
Age 1.02 0.46 1.02 0.23 1.01 0.67 1.04 0.56
BMI 0.87 0.028 NA NA NA NA NA NA
FRS(%) 1.04 0.35 1.01 0.75 NA NA NA NA
LVEF 0.97 0.044 NA NA NA NA 0.90 0.009
AC SSS 1.04 0.15 1.05 0.001 1.04 0.030 1.03 0.58
Clinical data + Non-attenuation correction
Gender 0.53 0.14 0.74 0.32 0.71 0.35 0.24 0.16
Age 1.02 0.43 1.02 0.21 1.01 0.63 1.05 0.51
BMI 0.88 0.038 NA NA NA NA NA NA
FRS(%) 1.03 0.37 1.00 0.83 NA NA NA NA
LVEF 0.97 0.056 NA NA NA NA 0.90 0.015
NAC SSS 1.05 0.047 1.05 <0.001 1.04 0.024 1.06 0.33
Clinical data + Attenuation correction
Gender 0.59 0.21 0.88 0.66 0.80 0.53 0.26 0.22
Age 1.03 0.39 1.03 0.10 1.01 0.50 1.03 0.69
BMI 0.88 0.040 NA NA NA NA NA NA
FRS(%) 1.03 0.48 1.00 0.87 NA NA NA NA
LVEF 0.97 0.055 NA NA NA NA 0.91 0.009
AC SSS group 1.30 0.31 1.41 0.011 1.32 0.08 1.43 0.57
Clinical data + Non-attenuation correction
Gender 0.54 0.15 0.81 0.48 0.76 0.45 0.21 0.16
Age 1.03 0.35 1.03 0.053 1.02 0.33 1.03 0.67
BMI 0.88 0.044 NA NA NA NA NA NA
FRS(%) 1.02 0.53 1.00 0.83 NA NA NA NA
LVEF 0.97 0.056 NA NA NA NA 0.90 0.010
NAC SSS group 1.61 0.14 1.48 0.011 1.31 0.12 1.84 0.41

AC SSS and NAC SSS were analyzed in two separate models due to significant correlation between AC SSS and NAC SSS.

* SSS group: classifying the severity of MPI by SSS 0–3, 4–8, 8–13, > 13.

** AC: attenuation correction; BMI: body mass index; FRS: Framingham risk score; gr: group; LVEF: left ventricular ejection fraction; NAC: non-attenuation correction; SSS: summed stress score.