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. 2021 Oct 26;16(10):e0258983. doi: 10.1371/journal.pone.0258983

Table 5. Multivariable analysis for all-cause mortality, composite of mortality and cardiovascular (CV)-related re-admission, CV-related re-admission and heart failure (HF) admission with SRS.

Overall Mortality Composite of Mortality & CV Re-admission CV Re-admission HF Admission
HR P value HR P value HR P value HR P value
Clinical data + Attenuation correction
Gender 0.59 0.22 0.81 0.47 0.82 0.57 0.42 0.41
Age 1.03 0.39 1.03 0.12 1.02 0.31 1.05 0.51
BMI 0.86 0.027 NA NA NA NA NA NA
FRS(%) 1.04 0.33 1.01 0.66 NA NA NA NA
LVEF 0.98 0.15 NA NA NA NA 0.90 0.002
AC SRS 1.06 0.041 1.05 0.016 1.02 0.48 0.89 0.30
Clinical data + Non-attenuation correction
Gender 0.54 0.15 0.75 0.33 0.80 0.54 0.45 0.45
Age 1.03 0.38 1.03 0.13 1.02 0.31 1.04 0.53
BMI 0.86 0.029 NA NA NA NA NA NA
FRS(%) 1.04 0.29 1.01 0.70 NA NA NA NA
LVEF 0.98 0.34 NA NA NA NA 0.90 0.002
NAC SRS 1.07 0.009 1.05 0.005 1.02 0.46 0.92 0.33
Clinical data + Attenuation correction
Gender 0.64 0.29 0.88 0.65 0.85 0.63 0.44 0.41
Age 1.02 0.41 1.03 0.10 1.02 0.24 1.07 0.38
BMI 0.87 0.030 NA NA NA NA NA NA
FRS(%) 1.03 0.42 1.01 0.62 NA NA NA NA
LVEF 0.98 0.17 NA NA NA NA 0.90 0.002
AC SRS group 1.45 0.06 1.24 0.06 1.03 0.84 0.46 0.13
Clinical data + Non-attenuation correction
Gender 0.60 0.23 0.83 0.51 0.81 0.56 0.47 0.50
Age 1.03 0.36 1.03 0.09 1.02 0.32 1.05 0.48
BMI 0.87 0.035 NA NA NA NA NA NA
FRS(%) 1.02 0.52 1.01 0.77 NA NA NA NA
LVEF 0.98 0.24 NA NA NA NA 0.90 0.003
NAC SRS group 1.51 0.06 1.23 0.035 1.11 0.50 0.69 0.41

AC SRS and NAC SRS were analyzed in two separate models due to significant correlation between AC SRS and NAC SRS.

* SRS group: Classifying the severity of MPI by SRS 0–3, 4–8, 8–13, > 13.

** AC: attenuation correction; BMI: body mass index; FRS: Framingham risk score; gr: group; LVEF: left ventricular ejection fraction; NAC: non-attenuation correction; SRS: summed rest score.