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. 2021 Oct 22;8:1269–1279. doi: 10.2147/JHC.S328198

Table 3.

Histopathologic Features of s-HCCs

Histologic Finding Metrics
Single tumor [%] 82.9% (136/164)
Multiple tumors [%] 17.1% (28/164)
Tumor size
 Range 1.2–17 cm
 Mean ± SD 4.2 ± 2.33 cm
Edmondson grade
 I 30.1%
 II 50.4%
 III 18.0%
 IV 1.5%
Grading
 G1 25.5% (58/227)
 G2 50.7% (115/227)
 G3 23.8% (54/227)
Background liver parenchyma
 Hepatitis 39.9% (117/293)
 Cirrhosis 28.3% (83/293)
 Normal liver parenchyma 11.8% (37/313)
 Steatosis 63.2% (36/57)
Irregular histopathological structure 97.6% (41/42)
Bulging of the tumor* 100% (51/51)
Capsule 26.3% (82/312)
Septum 85.6% (83/97)
Central scar 63.5% (40/63)
Venous invasion 32.6% (46/141)
Necrosis:
 Present 25.0% (58/232)
 Absent 75.0% (174/232)

Note: *For tumors located near the capsule.