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. 2021 Oct 25;59(1):1439–1449. doi: 10.1080/13880209.2021.1991386

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Effects of QLY granules on the expression of CXCL12/CXCR4 in spleen of AA rats. Expression of CXCL12 and CXCR4 level in spleen of AA rats. Representative immunohistochemical analyses of (A) CXCL12 and (B) CXCR4 expression in spleens, illustrating alterations in spleens of each group of rats (magnification, ×400). a: normal; b: model; c: QLY granules (1.35 g/kg); d: QLY granules (2.70 g/kg); e: QLY granules (5.40 g/kg); f: TG (10 mg/kg). Optical density value (ODV) of (C) CXCL12 and (D) CXCR4 in spleens markedly decreased in rats with AA following the administration of QLY granules and TG. Data are expressed as the mean ± SD, with 5 animals in each group. **p < 0.01 vs. normal, ^#p < 0.05 vs. model.