Waterfall plot according to randomized arm showing the sum of relative Curie score (Curie score after first course divided by baseline Curie score) minus 1 such that a value of 0 represents no change from baseline, a value of –1 represents a complete response by Curie score, and positive values represent increases in Curie score. A, B, and C correspond to arms A, B, and C. The heavy red line represents threshold for being considered to have had a partial response or better by Curie score.