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. 2021 Sep 27;12(10):6558–6570. doi: 10.1364/BOE.433281

Table 2. Prediction of clinicopathologically classified patients by the TACS + TCMF-score.

Subgroups  Predict grade1 (130) Predict grade2/3 (413) OR P-value AUC SEN SPE
Age
≤50 71 (54.6%) 242 (58.6%) 2.562 7.14E-13 0.836 0.875 0.696
>50 59 (45.4%) 171 (41.4%) 2.829 3.02E-10 0.884 0.856 0.721
Molecular subtype
Luminal A 41 (31.5%) 67 (16.2%) 3.509 2.27E-07 0.922 0.886 0.842
Luminal B 43 (33.1%) 181 (43.8%) 2.433 6.81E-08 0.831 0.881 0.613
HER2-enriched 27 (20.8%) 90 (21.8%) 2.294 6.26E-05 0.796 0.865 0.619
Triple-negative 19 (14.6%) 75 (18.2%) 2.242 0.002 0.844 0.859 0.667
Tumor size
≤2cm 67 (51.5%) 151 (36.6%) 2.592 7.08E-10 0.841 0.817 0.667
2-5cm 57 (43.8%) 228 (55.2%) 2.916 3.02E-12 0.875 0.898 0.756
>5cm 6 (4.6%) 34 (9.2%) 1.754 0.105 0.757 0.917 0.500
Nodal status
0 74 (56.9%) 196 (47.5%) 3.221 9.81E-13 0.867 0.869 0.719
1-3 24 (18.5%) 103 (24.9%) 2.042 3.67E-05 0.801 0.897 0.600
≥4 32 (24.6%) 114 (27.6%) 2.680 6.77E-06 0.897 0.855 0.800