Table 4. The performance comparison of different models for predicting pathologic grades. a .
| Model | Training cohort |
Validation cohort |
||||
|---|---|---|---|---|---|---|
| AUC (95%) | SEN (95%) | SPE (95%) | AUC (95%) | SEN (95%) | SPE (95%) | |
| Clinical | 71.7 (66.5-76.5) | 74.0 (68.2-79.1) | 58.7 (45.6-71.0) | 67.2 (60.5-73.4) | 77.1 (70.2-83.0) | 50.0 (32.9-67.1) |
| TCMF+TACS | 85.9 (81.6-89.4) | 88.7 (84.2-92.2) | 68.3 (55.3-79.4) | 86.3 (80.9-90.6) | 83.8 (77.6-88.9) | 77.8 (60.8-89.9) |
| combined model | 87.4 (83.3-90.8) | 85.3 (80.4-89.3) | 76.2 (63.8-86.0) | 87.4 (82.3-91.6) | 84.4 (78.2-89.3) | 75.0 (57.8-87.9) |
a
Abbreviations: AUC, area under the receiver operating characteristic curve; SEN, sensitivity; SPE, specificity.