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. 2021 Oct 22;14:5115–5129. doi: 10.2147/OTT.S329383

Figure 2.

Figure 2

Occurrence of colorectal cancer in female breast cancer patients/survivors. Well-coordinated interaction between the gut microbiome and host miRNAs is maintained within the host, but dysbiosis of gut microbiota and aberrant expression of several host miRNAs can cause malignancies such as breast and colorectal cancers. Alternatively, female breast cancer patients and/or survivors show a possible risk of having colorectal cancer. Levels of endogenous and/or exogenous sex hormones and differential behavior of some common set of miRNAs cause colorectal cancer in females with a history of breast cancer.