Table 1.

Typical parameters used in the TEM simulations, chosen to be consistent with parameters for a Thermo Fisher Scientific Titan Krios TEM [41].

parameter	description	value
E	energy	300 keV
Δf	defocus	2.5 µm
Cs	spherical aberration	2.7 mm
Cc	chromatic aberration	2.7 mm
ΔI/I	current spread	0.33 ppm
ΔV/V	voltage spread	0.80 ppm
ΔE	energy spread	0.8 eV
θc	source spread	0.1 mrad
dpx	pixel size	1 Å
ts	multislice z-slice thickness	5 Å
	potential approximation	Lobato et al. [42]
SE	beam damage sensitivity coefficient	0.022 A2/e−