Table 4.
Effect of BER and LMY on intestinal lesion score and morphology of broilers challenged with C. perfringens.
| Parameter | NC | PC | BER | LMY |
|---|---|---|---|---|
| ILS | 0.17 ± 0.26b | 2.25 ± 0.99a | 0.50 ± 0.45b | 0.33 ± 0.52b |
| Duodenum | ||||
| VH (μm) | 912.88 ± 42.92b | 881.46 ± 64.10b | 1101.84 ± 64.78a | 1136.73 ± 63.74a |
| CD (μm) | 188.87 ± 15.89 | 195.48 ± 12.16 | 193.96 ± 13.76 | 189.58 ± 12.78 |
| VH/CD | 4.87 ± 0.58b | 4.54 ± 0.60b | 5.72 ± 0.66a | 6.03 ± 0.70a |
| Jejunum | ||||
| VH (μm) | 808.48 ± 69.60 | 778.99 ± 65.77 | 819.97 ± 56.45 | 848.02 ± 67.40 |
| CD (μm) | 158.75 ± 9.82 | 171.81 ± 15.15 | 167.87 ± 11.55 | 158.48 ± 16.90 |
| VH/CD | 5.09 ± 0.63ab | 4.57 ± 0.59b | 4.89 ± 0.30ab | 5.38 ± 0.53a |
| Ileum | ||||
| VH (μm) | 589.94 ± 62.60 | 576.35 ± 37.11 | 608.62 ± 67.74 | 571.72 ± 55.61 |
| CD (μm) | 136.18 ± 11.88ab | 147.70 ± 11.75a | 136.42 ± 12.98ab | 130.94 ± 11.88b |
| VH/CD | 4.37 ± 0.68 | 3.92 ± 0.40 | 4.51 ± 0.76 | 4.40 ± 0.63 |
Each value represents the mean ± SD of six replicates. Values with no superscript letter or the same superscript letter are not significantly different (P > 0.05); those with different superscript letters are significantly different (P < 0.05). NC: negative control; PC: positive control; BER: berberine-treated; LMY: lincomycin-treated; ILS: intestinal lesion score; VH: villus height; CD: crypt depth; VH/CD: villus height: crypt depth.