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. 2021 Oct 19;2021:1698771. doi: 10.1155/2021/1698771

Figure 6.

Figure 6

The regulatory relationship and expression of SLCO4A1-AS1-miR-149-5p-STAT3 in gastric cancer. (a–c) STAT3 was the target gene of miR-149-5p, which was predicted by starBase database (https://starbase.sysu.edu.cn/) and verified by dual luciferase reporter gene. (d) STAT3 was elevated in gastric cancer tissues, detected by RT-qPCR (n = 46). Experiment was repeated three times independently. (e, f) Pearson correlation coefficient was used to analyze the relationship between STAT3 and SLCO4A1-AS1 (r = 0.142 and P < 0.05), as well as STAT3 and miR-149-5p (r = −0.622 and P < 0.001). Each experiment was repeated three times independently. ∗∗P < 0.01 versus blank; ##P < 0.01 versus adjacent tissue. STAT3, signal transducer and activator of transcription 3.