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DCA attenuates the expressions of key occludin and ZO-1 of TJ membrane proteins in vitro to maintain BBB integrity. (a–d) Western blotting assay of occludin and ZO-1 and the band strength of the respective protein relative to Tubulin in mouse brain. The mentioned results indicate that DCA inhibits ischemia-induced BBB destruction. ∗P < 0.05 and ∗∗P < 0.01. The comparison between cohorts is marked in the figure.
