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. 2022 Mar 1;42(2):178–187. doi: 10.3343/alm.2022.42.2.178

Table 2.

Performance of NephroCheck as a biomarker of AKI development added to the conventional variables at T0

Discrimination Reclassification
AUC (95% CI) P (vs. initial model*) NRI (%, 95% CI) P IDI (%, 95% CI) P
ED score + NC 0.71 (0.65-0.78) 0.023 33.8 (4.3-60.2) 0.012 2.4 (0.4-4.5) 0.02
eGFR + NC 0.65 (0.57-0.74) 0.14 27.4 (1.8-52.9) 0.036 2.3 (0.2-4.3) 0.031

The initial models are underlined, the updated models additionally included NC, P values are vs. the initial model.

Abbreviations: NRI, net reclassification improvement; IDI, integrated discrimination improvement; see Table 1.