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. 2021 Oct 26;11:21103. doi: 10.1038/s41598-021-00396-2

Table 2.

Clinical lymphedema stage and excess volume, fat mass, and lean mass.

Clinical International Society of Lymphology stage
Arm composition Stage 0 (n = 15) Stage 1 (n = 36) Stage 2a (n = 96) Stage 2b (n = 51) Stage 3 (n = 2) Multivariate linear regression
Mean ± SD Mean ± SD Mean ± SD Mean ± SD Mean ± SD Coefficient (95%CI) P-value
Volume (%) 2.00 ± 7.77 7.52 ± 10.51 36.01 ± 22.83 13.71 ± 16.09 42.98 ± 24.52 3.64 (0.09; 7.21)  = 0.04
Fat mass (%) 2.38 ± 17.21 9.72 ± 27.83 21.55 ± 34.58 30.48 ± 31.10 48.38 ± 66.06 7.23 (− 0.48; 14.95)  = 0.07
Lean mass (%) 2.44 ± 18.36 8.31 ± 23.16 35.37 ± 27.77 3.72 ± 21.26 79.57 ± 82.86 2.95 (− 17.61; 23.53)  = 0.77

This table shows the association between clinical lymphedema stage and excess volume, fat mass, and lean mass. The multivariate regression model was adjusted for age, BMI, arm dominance, lymphedema duration, and lymphedema latency. N = number of patients at each stage.

SD standard deviation.