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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Semin Cell Dev Biol. 2021 May 12;116:169–179. doi: 10.1016/j.semcdb.2021.05.002

Figure 1:

Figure 1:

Proposed network model of late-life depression (LLD). The model accounts for intrinsic connectivity within and extrinsic connectivity between the salience network, the default mode network (DMN) and the executive control network (ECN). Network-level disruptions in connectivity give rise to disrupted cognitive processes of LLD related to disrupted pursuits of goal-directed behaviors and maladaptive representations of affectively valenced stimuli.