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. 2021 Oct 13;8:738575. doi: 10.3389/fcvm.2021.738575

Table 4.

Associations of specific ECG characteristics and metabolic components with ECG-LVH in the obese and non-obese.

Sokolow-Lyon based ECG-LVH Cornell based ECG-LVH
Non-obesity Obesity Non-obesity Obesity
OR (95% CI) p -value OR (95% CI) p -value OR (95% CI) p -value OR (95% CI) p -value
ECG characteristics
Sinus bradycardia 1.27 (1.01–1.60) 0.04 0.89 (0.58–1.37) 0.59 1.13 (0.83–1.55) 0.43 0.85 (0.48–1.53) 0.60
Right axis deviation 0.53 (0.39–0.72) <0.001 1.06 (0.53–2.12) 0.87 2.72 (1.91–3.87) <0.001 1.49 (0.65–3.44) 0.34
ECG-LAE 1.02 (0.76–1.37) 0.90 1.09 (0.75–1.06) 0.64 1.45 (0.99–2.12) 0.053 1.14 (0.70–1.85) 0.61
First degree atrioventricular block 0.96 (0.49–1.88) 0.90 1.56 (0.74–3.28) 0.24 0.73 (0.25–2.08) 0.55 1.36 (0.55–3.33) 0.50
Inferior TWI 1.06 (0.51–2.21) 0.87 0.76 (0.38–1.50) 0.42 1.78 (0.76–4.19) 0.18 1.64 (0.78–3.41) 0.19
Metabolic components
Blood pressure ≥130/85 mmHg 1.22 (0.93–1.59) 0.15 1.45 (1.01–2.07) 0.04 1.15 (0.80–1.63) 0.45 1.70 (1.07–2.69) 0.02
Serum triglycerides ≥150 mg/dL 1.18 (0.85–1.64) 0.32 0.86 (0.57–1.29) 0.46 0.79 (0.50–1.25) 0.31 1.21 (0.75–1.94) 0.44
HDL-C <40 mg/dL 0.70 (0.51–0.96) 0.02 0.86 (0.57–1.30) 0.48 0.58 (0.35–0.96) 0.03 0.80 (0.48–1.34) 0.39
Waist circumference ≥90 cm 0.71 (0.48–1.05) 0.08 0.70 (0.45–1.07) 0.10 1.28 (0.77–2.13) 0.33 1.45 (0.78–2.70) 0.24
FPG ≥100 mg/dL 0.99 (0.75– 1.30) 0.92 1.25 (0.84–1.87) 0.27 0.86 (0.58– 1.27) 0.44 0.80 (0.48–1.33) 0.38

Data are presented as odds ratios (OR) and 95% CI (confidence intervals) using multiple logistic regression.

Model adjusted for age plus cigarette smoking status, alcohol drinking status and 3,000-m running categorical performance.

Sokolow-Lyon based ECG-LVH was diagnosed if (S-V1 or S-V2 + R-V5 or R-V6) ≥35 mm and Cornell based ECG-LVH was defined if R-aVL + S-V3 ≥18 mm, specifically for Asian young male adults.

ECG, electrocardiography; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; LAE, left atrial enlargement; LVH, left ventricular hypertrophy; TWI, T wave inversion.