Effect of alcohol on peripheral ghrelin levels in Ghsr KO and WT rats. (A) Effect of alcohol (1.5 g/kg, i.p.) on plasma acyl-ghrelin levels in Ghsr KO and WT rats. Data represent change in ghrelin secretion with alcohol treatment versus saline. N = 8–9/group. Treatment effect: P < 0.019, genotype effect: P = NS, and interaction effect: P = NS. (B) Effect of alcohol (1.5 g/kg, i.p.) on plasma des-acyl-ghrelin levels in Ghsr KO and WT rats. Data represent change in ghrelin secretion with alcohol versus saline treatment. N = 8–9/group. Treatment effect: P = NS, genotype effect: P = NS, and interaction effect: P = NS. Data are presented as mean ± SEM. *P < 0.05