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. 2021 Oct 13;9:739583. doi: 10.3389/fcell.2021.739583

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Copyright © 2021 Ding, Li, Han, Sun, Shen and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of a nomogram model integrated with the IRL signature. (A,B) Univariate and multivariate Cox analyses included different clinicopathologic features. (C,D) Multivariable ROC curves for overall survival (OS). (E) Nomogram model for predicting the 1-, 3-, and 5-year OS of GC patients. (F) Decision curve analysis of the OS-related nomogram. “None” indicates that all samples were negative without intervention and the net benefit was 0. “All” indicates that all samples were positive with intervention. (G) The bubble plot of gene set enrichment analysis (GSEA) results. (H) The enrichment plot of epithelial–mesenchymal transition.