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“Internal” cysteine-to-serine mutations do not affect the cell death signaling activity of PEG cross-linked Gal1 C130. (a) Flow cytometry scatterplots of Jurkat T cells treated with 3.75 μM Gal1 C130 + PEGbisMal or 3.75 μM Gal1 C130 no IC + PEGbisMal. (b) Percentage of dead Jurkat T cells when treated with 0.5, 2.5 or 3.75 μM Gal1 C130 + PEGbisMal or Gal1 C130 no IC + PEGbisMal.
