Table 4.

Sensitivity analysis of diagnostic accuracy of the saliva RT-LAMP test, as compared to several references.

Reference standard	Total, n	Positive samples, N	Sensitivity (95% CI)	Specificity (95% CI)
NPS RT-PCR ≥ 2 targets	1718	88	35% (26–45)	97% (96–98)
Symptoms	691	47	34% (24–46)	96% (95–98)
No symptoms	1027	41	36% (21–54)	97% (96–98)
NPS RT-PCR ≥ 1 target and Ct value < 32	1718	88	37% (27–47)	97% (96–98)
Symptoms	691	47	36% (24–49)	96% (94–98)
No symptoms	1027	41	38% (22–56)	97% (96–98)
Saliva RT-PCR ≥ 1 target	1640	85	30% (23–38)	97% (96–98)
Symptoms	662	45	28% (19–38)	96% (95–98)
No symptoms	978	40	33% (22–47)	98% (97–99)
NPS RT-PCR ≥ 1 target or Saliva RT-PCR ≥ 1 target	1648	87	28% (22–36)	97% (96–98)
Symptoms	667	47	27% (19–37)	97% (95–98)
No symptoms	981	40	30% (20–43	98% (97–99)
NPS RT-PCR ≥ 1 target or Saliva RT-PCR ≥ 1 target and Ct value < 32	1646	87	34% (26–42)	97% (96–98)
Symptoms	666	47	30% (21–41)	97% (95–98)
No symptoms	980	40	40% (26–55)	98% (97–99)
NPS antigen	1474	79	37% (28–47)	97% (96–98)
Symptoms	652	45	35% (24–46)	97% (95–98)
No symptoms	822	34	44% (26–62)	97% (96–98)

95% CI 95% confidence interval.