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. 2021 Oct 13;11:707618. doi: 10.3389/fonc.2021.707618

Figure 3.

Figure 3

Manganese (Mn)-based hybrid nanomaterials as theranostic agents and their application in tumor. (A) Schematic illustration of multifunctional nanocapsule and the systemic delivery of the self-sufficient theranostic nanoplatform (64). (B) Preparation and characterization of a core–shell MnS@Bi2S3-PEG nanostructure theranostic agents (70). (C) In vivo multimodal imaging (PA images, CT images, and MR images with the red circles mark the tumors) and corresponding signal analysis of tumor-bearing mice before and after intravenous injection of the monolayer bi-anchored Mn boride nanosheets (MBBN) (71). (D) In vivo therapeutic evaluation of FHCPC@MnO2 nanoflowers (polyphosphazene coated onto Fe3O4 nanoclusters, with MnO2 nanosheets as outer shell). Scale bar = 75 μm (72). PA, photoacoustic; FHCPC, coating multifunctional polyphosphazenes onto Fe3O4 nanoclusters and then growing manganese oxide nanosheets as outer shell; MBBN, Bi-anchored manganese boride nanosheets.