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. 2021 Oct 13;8:708096. doi: 10.3389/fnut.2021.708096

Figure 1.

Figure 1

Lactobacillus plantarum TWK10 attenuated the age-related decline in skeletal muscle strength by improving muscle quality. (A) Forelimb grip strength of young (n = 17) and aged mice (n = 16) was measured before administration. (B) Mice were treated with Lactobacillus plantarum TWK10 or PBS for 8 weeks, and forelimb grip strength was measured at week 0, week 4, and week 8. (C,D) Gastrocnemius muscles were harvested and subjected to measurements of muscle wet weight and glycogen levels. Data are represented as mean ± SD. Statistical differences among groups were analyzed by two-way ANOVA with the post-hoc Tukey-Kramer test. Different letters (a, b, c) indicate significant differences among groups, P < 0.05. Two group comparison was analyzed using the unpaired Student t-test. ***P < 0.001. (E) Pearson's correlation, after 8 weeks of TWK10/PBS administration, between grip strength and muscle glycogen levels in the young and aged mice.