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. 2021 Oct 13;12:698284. doi: 10.3389/fgene.2021.698284

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Copyright © 2021 Lin, Cheng, Liu, Wen, Kang, Xu, Shan, Chen, Li, Lai, Zhou, Hong, Hu, Li, Zhou, Geng and Jin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of differentially expressed autophagy-related genes (DE-ATGs) in low grade glioma (LGG) and enrichment analysis. (A) Volcano plot of DEGs in 529 tumor tissues of The Cancer Genome Atlas (TCGA) dataset and 1,035 normal samples from The Genotype-Tissue Expression (GTEx). The vertical axis indicates the–log [adjusted p value (adj. p value)], and the horizontal axis indicates the log2 [fold change (FC)]. The red dots represent upregulated genes, and the green dots represent downregulated genes (adj. p value <0.01 and |log2(FC)| > 1). (B) Venn diagram showing the 53 DE-ARGs (the intersection of the DEGs and ARGs). (C) Biological processes (BP), Cellular components (CC) and Molecular functions (MF) enriched in the DE-ARGs. (D) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways enriched in the DE-ARGs.