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. 2021 Oct 13;12:698284. doi: 10.3389/fgene.2021.698284

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Copyright © 2021 Lin, Cheng, Liu, Wen, Kang, Xu, Shan, Chen, Li, Lai, Zhou, Hong, Hu, Li, Zhou, Geng and Jin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Development of risk score based on the six autophagy-related gene signature of patients with TCGA-LGG validation set. (A) Kaplan-Meier plot for overall survival (OS) based on risk score of the six gene based signature of patients with TCGA-LGG validation cohort. (B) ROC curve for 5 years OS in validation cohort. (C) Heatmap of the six autophagy-related gene expression in the validation cohort. (D) Risk plot of each point sorted based on risk score. The black dotted line is the optimal cutoff (−7.009) classifying patients into low risk and high risk groups.