Table 1.
Demographics of patients with AD.
| Characteristic | AI with AD n = 13 (%) | AI without AD n = 107 (%) | P |
|---|---|---|---|
| Sex | 0.415 | ||
| Male | 6 (46) | 56 (52) | |
| Female | 7 (54) | 51 (48) | |
| Ethnicity | 0.342 | ||
| European | 7 (54) | 62 (58) | |
| South Asian | 2 (15) | 29 (27) | |
| African Caribbean | 1 (8) | 6 (5) | |
| Mixed Ethnicity | 1 (8) | 2 (2) | |
| Other | 0 (0) | 4 (4) | |
| Unknown | 2 (15) | 4 (4) | |
| Diagnosis | 0.004* | ||
| CAH | 3 (23) | 45 (42) | |
| Hypopituitarism | 2 (15) | 49 (46) | |
| Secondary to steroid Rx | 1 (8) | 3 (3) | |
| Addison’s/auto-immune | 0 | 5 (5) | |
| Unspecified | 5 (38) | 4 (4) | |
| Other | 2 (8) | 1 (1) | |
CAH, Congenital Adrenal Hyperplasia; P, P value for difference between groups calculated via Logistic regression. Nine patients did not have a specific diagnosis for the cause of their adrenal insufficiency.
*Results demonstrate a significant difference in underlying diagnoses between those with and without AD: CAH and Hypopituitarism are relatively underrepresented in the group with AD perhaps suggesting that those with an unclear diagnosis for their AI are at higher risk.