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. 2021 Oct 13;12:757518. doi: 10.3389/fneur.2021.757518

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Copyright © 2021 Ma, Sun, Zhang, Fan and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of MFN2 and localization of variants reported in this study. In red are novel variants on MFN2 detected in this study. In black are variants already reported. Nearly all variants were around the large GTPase domain near the N-terminus. GTPase, guanosine triphosphatase; HR1, heptad repeat 1; HR2, heptad repeat 2; PR, proline-rich; TM1, transmembrane domain 1; TM2, transmembrane domain 2.